Industrial pharmacy

General introduction of processes and used equipments

Mixing:-

It is a process in which two are more than two components are mixed in such a way that particles are adjacent to each other.

It is most common pharmaceutical operation used in all kinds of pharmaceutical industries.

Mixing can be done of:

• Liquid and liquid
• Solid and solids
• Solid and liquids
• Gases and liquids

Equipments used in mixing process:-

1. Silverson homogenizer

2. V-type mixer

Silverson homogenizer:-

• It is mostly used for mixing of suspension, emulsion and syrups.
• It has many parts:

1. Electric motor
2. Shaft
3. Stand
4. Blades
5. Head and fine mash.

Principal:-

It works on the principle of shear(cutting due to high speed).

Working:-

• Homogenizer is placed into the container containing emulsion.
• Speed of motor depends upon the product and quantity of sample.
• Through fine mesh, globules reach to blades.
• These blades out the large globule into smaller one.

V-type mixer:-

• It is used for large scale mixing of powders.
• Apparatus is made up of stainless steel.
• It has following parts:

1. V shaped container
2. Inlet
3. Outlet
4. Stand
5. Shaft
6. Motor

Principal:-

• It works on the principle of tumbling motion.

Working:-

• Different powders are placed in v- shape container from inlet.
• As blender rotates, material undergoes tumbling motion.
• After mixing ,material is collected in the bottom of V.
• Efficiency of mixer depends upon the speed of rotation.